Microbiology

Clostridium botulinum

Clostridium botulinum is clinically significant bacteria, which cause a very rare but a severe disease called “Botulism”. It produces a particular type of exotoxin that affects the nervous system by inhibiting the activity of neuromuscular junction. The botulinum toxin thus behaves as a neurotoxin that blocks the release of a neurotransmitter refers as “Acetylcholine”. Acetylcholine …

Clostridium botulinum Read More »

Botulism Disease

Botulism disease is caused by a bacterial agent (Clostridium botulinum) which produces an exotoxin. Clostridium botulinum causes bacterial food poisoning or intoxication by the release of exotoxin. Exotoxin acts as a neurotoxin that disables the normal functioning of the nervous system. Thus, an exotoxin produced by Clostridium botulinum refers as a Botulinum neurotoxin, which blocks the …

Botulism Disease Read More »

Excision Repair

Excision repair is one of the types of DNA repair systems, which is an enzymatic process and follows a cut, copy and paste mechanism. A cutting mechanism involves, removal of the damaged part or unusual bases by the specific enzymes like glycosylases and helicases. Then a copying mechanism consists of an enzyme DNA-polymerase I, uses …

Excision Repair Read More »

Adenovirus

Adenovirus is a type of DNA virus, which are medium-sized, non-enveloped and double-stranded. Adenovirus named after its isolation from the human adenoid tissue. It was first introduced by a scientist named Rowe who cultured and isolated adenovirus by the plasma tissue culturing. This group of virus can infect human, animals and birds. Adenovirus can cause …

Adenovirus Read More »